BMP7 Signaling in TGFb Receptor-2 deficient Stromal Cells Provokes Epithelial Carcinogenesis
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE106442
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资源简介：
Mouse forestomach fibroblasts were isolated from a wild-type (wt), a FSP-Cre;TGFBR2 lox/lox (TGFBR2cKO) mouse, and a FSP-Cre;TGFBR2 lox/lox; Smad4 lox/lox (TGFBR2/SMAD4 cKO) mouse and expanded in vitro. The cells were then harvested and processed for RNA purification. While wt and TGFBR2/SMAD4 cKO mice are healthy, the TGFBR2cKO mouse presents with forestomach cancer. Three samples; RNA samples from 1) wt fibroblast cell line 2) TGFbR2 cKO fibroblast cell line and 3) TGFbR2 & SMAD4 cKO fibroblast cell line.
创建时间：
2020-11-02
