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Study of the effect of JHU-083 on transcriptomics of gan diet induiced NASH mouse liver tissue

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NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP377319
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Male C57BL/6 mice aged 8 weeks were used for the study. After acclimatization, the mice were fed with either a chow or the GAN diet ad libitum for up to 26 weeks. The GAN mice were randomly divided into three subgroups at the beginning of Week 20 to receive JHU-083 by orally, or its vehicle . JHU-083 was administrated at 0.3 mg/kg or 0.1 mg/kg every day over the last 6 weeks.
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2022-05-28
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