Modification of genes regulating GABA receptor activity expression after oxycodone treatment.

Data are illustrated as follows: 1) Mean expression value for all groups; 2) Statistical analysis: results of variance analysis between vincristine and control: p-value and expression difference (vincristine – control); results of Student's t test between morphine and oxycodone in vincristine-treated rats: p-value and expression difference (morphine – oxycodone); results of Student's t test between morphine and oxycodone in control rats: p-value and expression difference (morphine – oxycodone). The three genes regulating GABA receptor activity expression were exclusively modified after analgesic treatment in vincristine-treated animals.