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Transfection of favorable genes into neuroblastoma cell lines

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NIAID Data Ecosystem2026-03-14 收录
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We previously used microarrays to show that a high expression of DHRS3, NROB1, and CYP26A1 predicts favorable neuroblastoma (NB) outcomes. Here, we investigated whether expression of these genes was associated with suppression of NB cells (SK-N-SH, NB12, and TGW) growth. We assessed morphology and performed growth, colony formation, and migration assays and RNA sequencing. Effects of transient expression of these genes were also assessed with a tetracycline-controlled expression (Tet-On) system.

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2022-10-12
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