Detection Novel miRNA/mRNA Potentially Involved in Renal Proximal Tubular Epithelial Cells under DM Using Next-Generation Sequencing and Bioinformatic Approaches. Detection Novel miRNA/mRNA Potentially Involved in Renal Proximal Tubular Epithelial Cells under DM Using Next-Generation Sequencing and Bioinformatic Approaches

MicroRNAs/mRNAs are hypothesized to play critical roles in the regulation of DM-induced proximal tubular injury. The aim of this study is to explore novel microRNAs and mRNA differentially expressed in RPTECs of a normal individual and a DM patient. Overall design: Next-generation sequencing for small RNA/mRNA of RPTECs with normal individual and DM