Crystal structure of the GluA2 ligand-binding domain (S1S2J) in complex with glutamate and positive allosteric modulator BPAM538
收藏Protein Data Bank Japan2024-11-13 更新2026-03-21 收录
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Crystal structure of the GluA2 ligand-binding domain (S1S2J) in complex with glutamate and positive allosteric modulator BPAM538 Descriptor: 4-cyclopropyl-7-(3-methoxyphenoxy)-2,3-dihydro-1$l^{6},2,4-benzothiadiazine 1,1-dioxide, ACETATE ION, GLUTAMIC ACID, ... Authors: Larsen, A.P, Frydenvang, K.A, Kastrup, J.S. Deposit date: 2017-07-10 Release date: 2018-01-03 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2 Å) Cite: 7-Phenoxy-Substituted 3,4-Dihydro-2H-1,2,4-benzothiadiazine 1,1-Dioxides as Positive Allosteric Modulators of alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors with Nanomolar Potency. J. Med. Chem., 61, 2018
创建时间:
2017-07-10



