Focal Adhesion Kinase catalytic domain in complex with bis-anilino pyrimidine inhibitor

Focal Adhesion Kinase catalytic domain in complex with bis-anilino pyrimidine inhibitor Descriptor: 2-{[5-CHLORO-2-({(1E,4R)-2-METHOXY-4-[(3R)-3-(METHYLAMINO)PYRROLIDIN-1-YL]CYCLOHEXA-2,5-DIEN-1-YLIDENE}AMINO)PYRIMIDIN-4-YL]AMINO}-N-(1-METHYLETHYL)BENZENESULFONAMIDE, FOCAL ADHESION KINASE 1 Authors: Lietha, D, Eck, M.J. Deposit date: 2008-08-28 Release date: 2008-09-09 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.31 Å) Cite: Crystal Structures of the Fak Kinase in Complex with Tae226 and Related Bis-Anilino Pyrimidine Inhibitors Reveal a Helical Dfg Conformation. Plos One, 3, 2008