Ratios to melanocytes are presented for the % of methylation in melanoma cell lines and melanocytes (MM/mel) and the fresh-frozen tumors (FT/mel). MM malignant melanoma. mel melanocytes. FT fresh-froz
Epigenetic modifiers are promising targets to improve therapies in patients with cancer. Targeting the methyltransferase DOT1L with small molecule inhibitors has shown promising effects on the control
The chromatin landscape of human mast cells is extensively reorganized upon FceRI crosslinking Overall design: Human mast cells were generated from peripheral blood-derived CD34+ cells with recombinan
