Manuscript

Original manuscript Assessment of intravascular volume status is difficult in critically ill patients. Evidence suggests that only 50% of hemodynamically unstable patients respond to a fluid challenge. Moreover, if cardiopulmonary function cannot compensate for the increase in preload, fluid loading may compromise microvascular perfusion, oxygen delivery and cause or aggravate peripheral and pulmonary edema. Inappropriate fluid expansion can increase morbidity and mortality thus making it important to accurately assess fluid responsiveness in critically ill patients. The volume responsiveness can be defined as a 15% increase in stroke volume (SV) or cardiac output (CO) after a 500-ml infusion.This study tested whether echocardiographic parameters can predict fluidresponsiveness in critically ill patients following a low volume 100-ml crystalloidsolution infusion over 1 minute原始研究手稿：重症患者的血管内容量状态评估极具挑战性。现有证据显示，仅50%的血流动力学不稳定患者可对液体负荷试验产生应答。此外，若心肺功能无法代偿前负荷的增加，液体输注可能损害微血管灌注、降低氧输送，甚至诱发或加重外周水肿与肺水肿。不恰当的液体扩容会增加发病率与死亡率，因此精准评估重症患者的液体反应性至关重要。液体反应性可定义为：在输注500ml液体后，患者每搏输出量（SV）或心输出量（CO）增加15%。本研究旨在验证经1分钟输注100ml小剂量晶体液后，超声心动图参数能否预测重症患者的液体反应性。

搜集汇总

背景与挑战

背景概述

该数据集研究危重病人液体反应性的预测方法，重点关注超声心动图参数在低容量晶体溶液输注后的应用效果。数据集属于麻醉学领域，采用开放许可协议。