DCN1 covalently bound to inhibitor 4
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DCN1 covalently bound to inhibitor 4 Descriptor: (2E)-N-[(2S)-2-cyclohexyl-2-({N-propanoyl-3-[6-(propan-2-yl)-1,3-benzothiazol-2-yl]-L-alanyl}amino)ethyl]-4-(morpholin-4-yl)but-2-enamide, Lysozyme, DCN1-like protein 1 chimera Authors: Stuckey, J.A. Deposit date: 2020-07-07 Release date: 2021-06-02 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.07 Å) Cite: Selective inhibition of cullin 3 neddylation through covalent targeting DCN1 protects mice from acetaminophen-induced liver toxicity. Nat Commun, 12, 2021
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2020-07-07
