Determine the genome-wide localization of histone and histone marks in different stages of D. discoideum
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE137599
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We report the chromatin immunoprecipitation followed by next generation sequencing (ChIP-seq) on H3, H3K4me1, H3K4me3, H3K9me3, H3K27ac, H3K27me3, and H3K36me3. ChIP-seq were sequenced to a depth of at least 8 million total reads/sample. We found that H3K4me3, H3K27ac and H3K4me1 show separation between unicellular and multicellular stages in principal component analysis (PCA); other marks were unable to show a clear separation in PCA. Examine the localizaiton of histone marks and nucleosome postioning in D. discoideum (AX2) thorughout the genome
创建时间：
2021-07-21
