Data from publication "Two new plasmid post-segregational killing mechanisms for the implementation of synthetic gene networks in E. coli." Fedorec et. al. iScience 2019
Wilms Tumor Protein (WT1) ZnF2-4 Q369H in complex with carboxylated DNA Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*(1CC)P*GP*T)-3'), DNA (5'-D(*TP*AP*(5CM)P*GP*CP*CP*CP*AP*CP*GP*C)
Data from publication "Two new plasmid post-segregational killing mechanisms for the implementation of synthetic gene networks in E. coli." Fedorec et. al. iScience 2019
Using mouse models of several recessive and putative dominant-negative patient mutations we were able to dissect the mechanisms that underlie the recessive and dominant-negative capacities of the corr