Patients enrolled in the study, type and number of oral mucosa subsites that underwent biopsy and were analyzed by hr DNA-FCM and aCGH.

1 Non-dysplastic oral potentially malignant disorder.2 Dysplastic oral potentially malignant disorder3 Oral squamous cell carcinoma, OSCC.a 155 females and 137 males; median age 66.9 (range 19.8–93.8) and 60.3 (range 18.5–86.3) years, respectively. Three hundred thirty one OPMDs/OSCCs oral subsites of 292 patients were sampled by single or multiple biopsies yielding 522 bioptic samples (see also Table 1). The nuclei suspensions of a subset of 145 bioptic samples obtained from 99 oral mucosa subsites of 99 of these 292 patients were also processed for DNA extraction and subsequent aCGH analysis. Therefore, the DNA index (DI) was also measured for each of the 145 DNA samples processed for aCGH. A single OPMD or OSCC for each patient was examined by aCGH.b 52 females and 42 males; median age 70.5 (range 19.8–93.8) and 60.3 (range 18.5–86.3) years, respectively.C The bioptic samples of 5 patients were removed from the statistical analysis because they did not comply with the aCGH quality control criteria.Patients enrolled in the study, type and number of oral mucosa subsites that underwent biopsy and were analyzed by hr DNA-FCM and aCGH.