Datasets with Entropy-Based Similarity Scores of Multiple Sequence Alignments

This dataset collection accompanies the study on machine learning-based prediction of entropy scores from multiple sequence alignments. This repository includes simulated and reference datasets (Trees, DATASET, DATASET200), as well as BALiBASE and HOMSTARD benchmarks. Aligned sequences were generated using MAFFT, MUSCLE, and DIALIGN; results and scores are stored in CSV and Excel formats. Pre-trained models (CNN, ANN, Polynomial) and analysis results are also provided for further evaluation.