<b>Combining</b> <b>Sequential Organ Failure Assessment score and C-reactive protein-albumin-lymphocyte index in evaluating the prognosis of adult patients with septic shock</b>

The clinical data of 132 adult patients with septic shock admitted to the Critical Care Department of Zhongshan Hospital, Fudan University (Xiamen Branch) between January 1, 2019, and December 31, 2023, were retrospectively collected by reviewing the medical records. The data from the initial 3 years were used to construct a training set while the data from the final year were used to construct a validation set. Patients were divided into two groups based on survival during hospitalization for 28 days: the survival and death groups. The following clinical information was collected from the data of both groups: (1) demographic factors (including age and sex), pulse rate, blood pressure, level of consciousness (evaluated using the Glasgow Coma Scale [GCS]), complications (including diabetes mellitus, hypertension, chronic obstructive pulmonary disease [COPD], and coronary heart disease), and personal history of malignant tumors were recorded; (2) laboratory results obtained in the ICU including white blood cell count (WBC), lymphocyte count (L), platelet count (PLT), hemoglobin level (HB), total bilirubin level (TBIL), albumin level (ALB), sodium ion (Na), lactic acid (Lac), blood urea nitrogen (BUN), potassium ion (K), creatinine (CR), procalcitonin (PCT), C-reactive protein (CRP), and oxygenation index (PaO2 [P]/FIO2 [F]); and (3) renal replacement therapy and mechanical ventilation received during hospitalization. Finally, (4) APACHE Ⅱ score, SOFA score, and the CALLY index ([Albumin {g/L} × Lymphocyte count {×109/L}/CRP {mg/L}] × 100) [16] were collected and scores were calculated based on the initial data obtained within the previous 24 hours.