Characterization of A Novel Mengingoencephalomyelitis Associated with Vimentin IgG Autoantibodies

Autoantibodies are crucial for diagnosing central nervous system (CNS) autoimmune disorders. In autoimmune astrocytopathy, autoantibodies targeting astrocytes, such as those against glial fibrillary acidic protein (GFAP) or aquaporin protein 4 (AQP4), serve as indispensable diagnostic markers. Nevertheless, the diagnostic process remains challenging for patients who exhibit astrocytic reactivity on immunological tests but lack detectable specific autoantibodies