Ipilimumab-induced gastrointestinal, pancreatic and hepatic reactions.

*case is detailed in the result section. alisted treatments are systemic treatments unless otherwise specified. btumor free high-risk stage III melanoma (AJCC 2009); adjuvant administration of ipilimumab. cstage IV metastatic disease (AJCC 2009). M indicates male; F, female; TVP, polychemotherapy with temozolomide+vinblastin+carboplatin; TKI, tyrosine kinase inhibitor RAF265; ALT, alanine transaminase; AST, aspartate transaminase; GGT, gamma-glutamyl transferase; LN, lymph nodes; IFN-α, interferon-α; DTIC, dacarbazine; PR, partial response; SD, stable disease; PD, progressive disease.