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Elf3 regulated transcriptome dynamics in mesenchymal to epithelial transition

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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA693989
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The transcription factor Elf3 is critical for a proper mesenchymal to epithelial transition. It is involved in the regulation of Grhl3, an essential regulator of Cdh1 expression. Moreover, the absence of Elf3 results in mislocalized E-cadherin, and eventually failure of MET. We performed RNA-seq analysis of NMuMG cells after the siRNA-mediated depletion of Elf3 and compared to control cells.
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2021-01-22
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