首页/数据集/Additional file 1 of Distinct molecular pathways leading to dosage-dependent temozolomide resistance in GBM stem cells

Additional file 1 of Distinct molecular pathways leading to dosage-dependent temozolomide resistance in GBM stem cells

NIAID Data Ecosystem2026-05-10 收录

胶质母细胞瘤耐药性

肿瘤干细胞分子通路

数据链接：

https://figshare.com/articles/dataset/Additional_file_1_of_Distinct_molecular_pathways_leading_to_dosage-dependent_temozolomide_resistance_in_GBM_stem_cells/31550875 数据链接链接失效反馈

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资源简介：

Supplementary Material 1

应用场景：

创建时间：

2026-02-24

胶质母细胞瘤耐药性

RNA表达谱

Glioblastoma multiforme (GBM) is the most common and aggressive primary human brain tumor. Although comprehensive therapies combining radiotherapy and chemotherapy after surgery can prolong survival,

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Activation of STAT3 through SRC and EGFR Drives Resistance to a Mitotic Kinesin Inhibitor in Glioblastoma

胶质母细胞瘤耐药性

靶向治疗信号通路

The outcome for patients afflicted with glioblastoma (GBM), the most common and malignant of primary brain tumors in adults, has changed little despite decades of clinical, translational, and basic re

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Additional file 10 of Drug resistant glioblastoma stem cells exhibit enriched stemness signatures and share extracellular matrix overexpression

胶质母细胞瘤耐药性

肿瘤干细胞差异表达基因

Additional file 10. Differentially expressed genes. Complete list of the differentially expressed genes between the drug-resistant and drug-sensitive GSC cultures.

Figshare2025-10-27 更新50

Drug resistance in glioblastoma. Homo sapiens

胶质母细胞瘤耐药性

烷化剂耐药性

Combined model of in vitro and in vivo resistance to alkylating agents (BCNU and Temozolomide) in glioblastoma multiforme. Three matched pairs of surgical specimens from initial (DI, ME, LX) and repea

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Rational targeting of dynamic tumor subclones in relapsing human glioblastoma

胶质母细胞瘤耐药性

肿瘤亚克隆动态分析

Glioblastoma therapy relies on the alkylating drug temozolomide (TMZ) administered to irradiated patients post-neurosurgery, which increases overall survival but cannot prevent fatal disease relapse.

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Additional file 1 of Distinct molecular pathways leading to dosage-dependent temozolomide resistance in GBM stem cells

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