Structure of IGF-1R kinase domain complexed with a benzimidazole inhibitor
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Structure of IGF-1R kinase domain complexed with a benzimidazole inhibitor Descriptor: 3-[5-(1H-IMIDAZOL-1-YL)-7-METHYL-1H-BENZIMIDAZOL-2-YL]-4-[(PYRIDIN-2-YLMETHYL)AMINO]PYRIDIN-2(1H)-ONE, Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) Authors: Sack, J.S, Jacobson, B.L. Deposit date: 2007-01-12 Release date: 2007-05-01 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2 Å) Cite: Discovery and initial SAR of 3-(1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-ones as inhibitors of insulin-like growth factor 1-receptor (IGF-1R). Bioorg.Med.Chem.Lett., 17, 2007
创建时间：
2007-01-12
