CTE RNASeq association with APOE and TMEM. It is known that APOE is a risk factor of CTE. This study will look at differences between CTE stages - mild and severe, including associations with age, APO
We have sequenced MSA brain as follows1. Mate pair sequence for one case, substantia nigra and cerebellum2. Exome sequences from 13 cases3. Single cell low coverage WGS, 170 cells passing QC and analy
The goal of this study is to determine the effects of targeted RNA editing in the hippocampus of a mouse model of Rett syndrome. Mice containing a patient G>A mutation in Methyl CpG binding Protein 2
We used microarrays to investigate whether transcriptional dysregulation in hypothalamus is caused by expression of the huntingtin (HTT) protein We used two different Huntington's disease mouse models
Brain-specific SIRT6-KO mice present increased DNA damage, learning impairments, and neurodegenerative phenotypes, placing SIRT6 as a key protein in preventing neurodegeneration. In the aging brain, S
