Percentage of bistable parameter sets (MA) for increasing values.

The percentage of parameter sets generating a bistable multisite phosphorylation system with or without scaffold is described for using full mass action kinetics (MA) and classified according to the value of the enzymatic reactions. The vary from to and are grouped in 10-fold regimes. Each entry in the table was created using 500 independent parameter sets. In order to ensure a sufficient difference between the steady states, we assume a fold ratio larger or equal than 5 between the largest and the smallest steady state of , i.e.\.