MetaCyc

MetaCyc is a curated database of experimentally elucidated metabolic pathways from all domains of life. MetaCyc contains pathways involved in both primary and secondary metabolism, as well as associated metabolites, reactions, enzymes, and genes. The goal of MetaCyc is to catalog the universe of metabolism by storing a representative sample of each experimentally elucidated pathway. MetaCyc applications include: Online encyclopedia of metabolism, Prediction of metabolic pathways in sequenced genomes, Support metabolic engineering via enzyme database, Metabolite database aids. metabolomics research.

MetaCyc乃是一个精心编纂的生命代谢途径数据库，汇聚了源自生命各个域的实验阐明代谢途径。该数据库囊括了涉及初级与次级代谢的途径，以及相关的代谢物、反应、酶和基因。MetaCyc旨在通过存储每一条实验阐明途径的代表性样本，对代谢宇宙进行详尽著录。MetaCyc的应用领域包括：代谢学在线百科全书、测序基因组中代谢途径的预测、通过酶数据库支持代谢工程，以及作为代谢组学研究辅助的代谢物数据库。

搜集汇总

背景与挑战

背景概述

MetaCyc是一个经过人工整理的代谢途径数据库，收录了来自所有生命领域的实验验证代谢途径，包括初级和次级代谢相关数据。该数据库旨在作为代谢百科全书，支持基因组学、代谢工程和代谢组学研究，包含超过3,000条途径和数万个反应与代谢物，由美国研究机构资助并提供开放访问。