A subset of human papillomavirus (HPV) infections is causally related to the development of human epithelial tumors and cancers. Like a number of pathogens, HPV entry into target cells is initiated by
R-loops are trimeric nucleic acid structures that form when an RNA molecule hybridizes with its complementary DNA strand, displacing the opposite strand. These structures regulate transcription as wel
SET is a multifunctional histone-binding oncoprotein that regulates transcription by an unclear mechanism. Here, we show that SET enhances estrogen-dependent transcription. SET knockdown abrogates tra
Wildtype mouse embryo fibroblasts were treated with the histone deacetylase inhibitor trichostatinA 8 hours before being incubated with the radiomimetic drug neocarzinostatin (NCS) for 1hour prior to
