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资源简介：
OPRM1 SNPs and associated outcomes.
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创建时间：
2021-12-15
相关数据集
Opioids as Substrates and Inhibitors of the Genetically Highly Variable Organic Cation Transporter OCT1
Genetic variants in the hepatic uptake transporter OCT1, observed in 9% of Europeans and white Americans, are known to affect pharmacokinetics and efficacy of tramadol, morphine, and codeine. Here, we
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Additional file 2 of Genetic variants modulate gene expression statin response in human lymphoblastoid cell lines
Additional file 2: Table S2. Lead endogenous eQTLs per gene in LCLs from African American ancestry subset.
Figshare2020-08-13 更新60
Ultrastructural damage is strongly reduced in persephone homozygotes versus wild-type siblings after neomycin exposure.
n = number of fish in each category. Damage scale: A = All hair cells of the neuromast appear normal. B = Slight mitochondrial swelling (modest within range of mock-treated controls). C = One or more
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Genetic Analysis of Human Traits In Vitro: Drug Response and Gene Expression in Lymphoblastoid Cell Lines
Lymphoblastoid cell lines (LCLs), originally collected as renewable sources of DNA, are now being used as a model system to study genotype–phenotype relationships in human cells, including searches fo
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Oxycodone self-administration and genetic background exert community-specific effects in the gut microbiome
Relevance: The gut microbiome and genetic factors contribute to OUD-related phenotypes, including oxycodone-induced analgesia and reward. Here, we examine the effects of genetic background and oxycodo
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