Specific miRNA in immune thrombocytopenia (ITP) was screened to explore its intervention effects and mechanisms in ITP. MTT assay and CFSE staining were used to detect the effects of gradient concentr
To investigate the function and mechanism of chi-miR-99b-3p in goat, we firstly demonstrated the role of chi-miR-99b-3p as a myogenic miRNA in regulating skeletal muscle development. Overexpression of
MiR-21 was identified as a gene whose expression correlated with the extent of metastasis of murine mammary tumours. Since miR-21 is recognized as being associated with poor prognosis in cancer, we in
MicroRNAs (miRNAs) regulate the expression of mRNAs through sequence-specific binding into their 3' untranslated region (UTR). The seed sequence of miRNAs is the key determinant to recognize the targe
To explore the mechanism of miR-582-5p affecting NSC stemness, we transfected miR-582-5p mimics in cultured neurospheres from E14.5 embryos, and performed RNA sequencing. The results showed that 60 ge
