Visium Spatial Transcriptomics of a murine model of IPMN

Pancreata were collected from two Kras;Gnas mice and analyzed by Visium Spatial Gene Expression to evaluate the transcriptional profile associated with NKX6-2 that was observed in the human IPMN samples. Overall design: Samples were collected from mice at 15 and 25 weeks post doxycycline treatment and were flash frozen. The samples were then cryosectioned and analyzed with the Visium Spatial Gene Expression platform from 10x genomics.