Replication Data for: A Critical Analysis of Computational Protein Design with Sparse Residue Interaction Graphs

The following contains the data and results used in the following paper: Swati Jain, Jonathan D. Jou, Ivelin S. Georgiev, and Bruce R. Donald. A Critical Analysis of Computational Protein Design with Sparse Residue Interaction Graphs. PLoS Comp Biol. 2017, In press. To test the hypothesis and results of sparse residue interaction graphs as presented in this manuscript, the archived version of the code can be found at: https://github.com/donaldlab/OSPREY_SparseAStar . For new empirical designs, we recommend using the latest version of OSPREY 2.1 available at http://www.cs.duke.edu/donaldlab/osprey.php that includes continuous sidechain and backbone flexibility, ensemble-based design, and new and faster methods to calculate energy functions.