A XEN-like state bridges somatic cells to pluripotency during chemical reprogramming

ChEBI2015-12-09 更新2026-07-12 收录

化学重编程

细胞命运转变

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-73631 数据链接链接失效反馈

官方服务：

资源简介：

A XEN-like state bridges somatic cells to pluripotency during chemical reprogramming

创建时间：

2015-12-09

An alternative transcriptome shapes cell fate transitions in yeast (TES-seq). An alternative transcriptome shapes cell fate transitions in yeast (TES-seq)

细胞命运转变

替代转录组调控

Alternative mRNA isoforms and long noncoding RNAs (lncRNA) make up a large fraction of the transcriptome and play key functions in cell-fate programming. These transcripts often initiate upstream of c

NIAID Data Ecosystem80

Tracing the conversion process for primordial germ cells to pluripotent stem cells

干细胞重编程

细胞命运转变

The overall gene expression profiles revealed by this system provide novel insight into how pluripotency is acquired in germ-committed cells. In the study presented here, we employed FACS sorting to p

NIAID Data Ecosystem40

Direct neuronal reprogramming by temporal identity factors

神经元重编程

细胞命运转变

Temporal identity factors are sufficient to reprogram developmental competence of neural progenitors and shift cell fate output, but whether they can also reprogram the identity of terminally differen

NIAID Data Ecosystem20

Elf3 regulated transcriptome dynamics in mesenchymal to epithelial transition

细胞命运转变

转录组调控

The transcription factor Elf3 is critical for a proper mesenchymal to epithelial transition. It is involved in the regulation of Grhl3, an essential regulator of Cdh1 expression. Moreover, the absence

NIAID Data Ecosystem60

CD3254-RXRa Axis Promotes Chemical Reprogramming via RNA Exosome-Mediated MMVL30 Degradation and Inflammation Suppression [CUT&Tag]

化学重编程

CUT&Tag染色质分析

We show that CD-RXRa axis significantly promotes mouse chemical reprogramming of fibroblasts. To identify the molecular mechanisms of CD-RXRa axis in chemical reprogramming, we construct Flag-Rxra-OE

NIAID Data Ecosystem30

A XEN-like state bridges somatic cells to pluripotency during chemical reprogramming

资源简介：

相关数据集