First commenting round on the draft updated Test Guidelines 488 and 470 on in vivo gene mutation assays
收藏Organisation for Economic Co-operation and Development2026-04-11 收录
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https://www.oecd.org/en/events/public-consultations/2024/12/first-commenting-round-on-the-draft-updated-test-guidelines-488-and-470-on-in-vivo-gene-mutation-assays.html
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Most genetic toxicology Test Guidelines include three equal considerations when assessing whether a response is positive or negative, i.e. (i) a statistically significant increase from the concurrent negative control, (ii) a concentration/dose related response and (iii) the comparison to the historical negative control distributions, for assessing...
