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Crystal structure of the mutated EGFR kinase domain (G719S/T790M) in complex with gefitinib

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Protein Data Bank Japan2023-11-01 更新2026-03-21 收录
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https://pdbj.org/mine/summary/3ug2
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Crystal structure of the mutated EGFR kinase domain (G719S/T790M) in complex with gefitinib Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Epidermal growth factor receptor, Gefitinib Authors: Parker, L.J, Handa, N, Yoshikawa, S, Kukimoto-Niino, M, Shirouzu, M, Yokoyama, S. Deposit date: 2011-11-02 Release date: 2012-03-07 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural basis for the altered drug sensitivities of non-small cell lung cancer-associated mutants of human epidermal growth factor receptor Oncogene, 32, 2013
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2011-11-02
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