Analyzed HEK293, K562, and HCT116 Repair Outcomes

Figshare2018-08-30 更新2026-04-08 收录

DNA损伤修复

细胞遗传学

数据链接：

https://figshare.com/articles/Analyzed_HEK293_K562_and_HCT116_Repair_Outcomes/6957197/1 数据链接链接失效反馈

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资源简介：

Here are all analyzed files and scripts used to analyze previously published DNA repair data form VanOverbeek et al 2016.

创建时间：

2018-08-30

Data_Sheet_1_TRF1 Depletion Reveals Mutual Regulation Between Telomeres, Kinetochores, and Inner Centromeres in Mouse Oocytes.PDF

染色体生物学

细胞遗传学

In eukaryotic chromosomes, the centromere and telomere are two specialized structures that are essential for chromosome stability and segregation. Although centromeres and telomeres often are located

NIAID Data Ecosystem60

p38-MK2 regulate RNA metabolism after UV light-induced DNA damage

DNA损伤修复

转录调控

Ultraviolet (UV) light induces the formation of bulky UV photoproducts in the genome that interfere with DNA replication and transcription. It is well-established how human cells repair UV light-induc

NIAID Data Ecosystem20

Transcriptome analysis of IR-treated HL-60 cells (shCtrl and shPTIP)

DNA损伤修复

基因表达调控

To explore the underlying molecular mechanisms behind DNA damage repair, gene expression profiles of shCtrl- and shPTIP (#1 and #2)-transduced HL-60 cells at 0 min and 180 min after IR were examined b

NIAID Data Ecosystem10

Discovery of Isaindigotone Derivatives as Novel Bloom’s Syndrome Protein (BLM) Helicase Inhibitors That Disrupt the BLM/DNA Interactions and Regulate the Homologous Recombination Repair

DNA损伤修复

抗癌药物设计

Homologous recombination repair (HRR), a crucial approach in DNA damage repair, is an attractive target in cancer therapy and drug design. The Bloom syndrome protein (BLM) is a 3′–5′ DNA helicase that

NIAID Data Ecosystem40

C. thermocellum UvrA in complex with DNA with a fluorescein modification and ADP (basal conformation)

DNA损伤修复

DNA复合物

C. thermocellum UvrA in complex with DNA with a fluorescein modification and ADP (basal conformation)

NIAID Data Ecosystem10