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Crystal structure of human CDK2 complexed with a thiazolidinone inhibitor

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Protein Data Bank Japan2024-05-08 更新2026-03-21 收录
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Crystal structure of human CDK2 complexed with a thiazolidinone inhibitor Descriptor: 2-IMINO-5-(1-PYRIDIN-2-YL-METH-(E)-YLIDENE)-1,3-THIAZOLIDIN-4-ONE, CELL DIVISION PROTEIN KINASE 2, CHLORIDE ION Authors: Richardson, C.M, Dokurno, P, Murray, J.B, Surgenor, A.E. Deposit date: 2007-05-14 Release date: 2007-06-26 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Discovery of a Potent Cdk2 Inhibitor with a Novel Binding Mode, Using Virtual Screening and Initial, Structure-Guided Lead Scoping. Bioorg.Med.Chem.Lett., 17, 2007

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2007-05-14
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