Mutant p53 Shapes the Enhancer Landscape of Cancer Cells in Response to Chronic Immune Signaling
收藏NIAID Data Ecosystem2026-05-26 收录
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资源简介：
We establish a mechanism by which chronic TNF-a signaling orchestrates a functional interplay between mutant p53 and NFkB that underlies altered patterns of cancer promoting gene expression. Overall design: examination of various histone mark accumulation; mutp53, NFkB, RNAPII binding; and nascent transcription upon chronic TNF signaling in SW480 colon cancer cells
创建时间：
2018-08-15
