Chenonceau deep white matter connectivity: mesoscopic MRI deep phenotyping of a post-mortem human brain at 7 and 11.7 Tesla

This dataset contains all the deep white matter bundles extracted from the diffusion MRI images of the Chenonceau dataset. The Chenonceau dataset consists of in-depth MRI acquisitions of a single post-mortem human brain. The brain was scanned piece by piece in two ultra-high-field preclinical MRI systems at 7 and 11.7 Tesla to achieve resolutions ranging from 200 µm to 100 µm. Once fully reconstructed, global tractography was performed on the entire brain using ExaTract, which leverages high-performance computing resources to address computational bottlenecks in the tractography algorithm. To do so, local diffusion ODFs were computed from diffusion MRI data acquired at a shell b=8000 s/mm² and 200 µm resolution, and a high-resolution tractography domain was delineated from multi-contrast quantitative MRI data. Deep white matter bundles were extracted from the entire tractogram based on distance comparison from the Herlin atlas. This dataset is made available under the CC BY-NC-SA 4.0 License, whose text is fully available at https://creativecommons.org/licensesby-nc-sa/4.0/