Homologous recombination repair (HRR), a crucial approach in DNA damage repair, is an attractive target in cancer therapy and drug design. The Bloom syndrome protein (BLM) is a 3′–5′ DNA helicase that
Ultraviolet (UV) light induces the formation of bulky UV photoproducts in the genome that interfere with DNA replication and transcription. It is well-established how human cells repair UV light-induc
To explore the underlying molecular mechanisms behind DNA damage repair, gene expression profiles of shCtrl- and shPTIP (#1 and #2)-transduced HL-60 cells at 0 min and 180 min after IR were examined b
Aminofluorene DNA adduct at the pre-insertion site of a DNA polymerase Descriptor: 2-AMINOFLUORENE, DNA polymerase I, DNA primer strand, ... Authors: Hsu, G.W, Kiefer, J.R, Becherel, O.J, Fuchs, R.P.P
