Index of Datasets: Dynamic representation of appetitive and aversive stimuli in nucleus accumbens shell D1- and D2-medium spiny neurons

Dataset Title: Dynamic representation of appetitive and aversive stimuli in nucleus accumbens shell D1- and D2-medium spiny neurons

Authors: Ana Verónica Domingues, Tawan T. A. Carvalho, Gabriela J. Martins, Raquel Correia, Bárbara Coimbra, Ricardo Gonçalves, Marcelina Wezik, Rita Gaspar, Luísa Pinto, Nuno Sousa, Rui M. Costa, Carina Soares-Cunha & Ana João Rodrigues.

LAB: Reward & Aversion Lab (https://reward-aversion.org/)Address: Life and Health Sciences Research Institute (ICVS), Campus de Gualtar, 4710-057 Braga, Portugal.

Summary: This dataset contains single cell calcium imaging recordings of D1- and D2-MSNs in the nucleus accumbens shell of freely-moving mice during an appetitive and aversive Pavlovian conditioning protocol. The data was collected using one-photon microscopy and processed with CaImAn and IDPS software. The data can be used to study the differential response of D1- and D2-MSNs to conditioned stimulus (e.g. predictive cues) and unconditioned stimuli (e.g. sucrose, condensed milk, tail lift and foot-shock).

Keywords: single cell calcium imaging, pavlovian conditioning, D1-MSNs, D2-MSNs, nucleus accumbens, mice, appetitive and aversive conditioning.

Dataset Components:

1. Appetitive conditioning - Days 1 to 3   DOI: 10.5281/zenodo.10688739

2. Appetitive conditioning - Days 4 to 6   DOI: 10.5281/zenodo.10694889

3. Appetitive conditioning - Days 7 and 10   DOI: 10.5281/zenodo.10779637

4. Fear conditioning - Days 1 to 3   DOI: 10.5281/zenodo.11547656

5. US exposures   DOI: 10.5281/zenodo.11644255

6. Omission   DOI: 10.5281/zenodo.12676161

7. Extinction   DOI: 10.5281/zenodo.12826917

Each component can be accessed using the provided DOI. For more information on each dataset, please visit the respective Zenodo repository page.

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