Target to cerebellum ratios in discrete regions of the rat brain following administration of [¹²⁵I]WYE-230949 (n = 4 to 5 for all groups) determined by ex vivo autoradiography.

The cerebellum was used as the non-specific reference region. *p<0.05, ***p<0.001 lower specific binding ratios in anaesthetised compared to conscious rats at both time points, †p<0.05, ††p<0.01, †††p<0.001 higher specific binding ratios at 120 minutes compared to 30 minutes in both conscious and anaesthetised rats, (mean ±S.E.M.), n = 4 to 5 for all groups, data analysed by 2-way ANOVA. Target to cerebellum ratios in discrete regions of the rat brain following administration of [125I]WYE-230949 (n = 4 to 5 for all groups) determined by ex vivo autoradiography.