Expression profiling of human adult postmortem brain tissue from subjects with bipolar disorder and healthy controls

Bipolar affective disorder is a severe psychiatric disorder with a strong genetic component but unknown pathophysiology. We used microarray technology (Affymetrix HG-U133A GeneChips) to determine the expression of approximately 22 000 mRNA transcripts in post-mortem brain tissue (dorsolateral prefrontal cortex and orbitofrontal cortex) from patients with bipolar disorder and matched healthy controls. This SuperSeries is composed of the SubSeries listed below. Refer to individual Series