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Structure of VIM-2 with 2-Mercaptomethyl-thiazolidine D-syn-1b

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Protein Data Bank Japan2024-01-31 更新2026-03-21 收录
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Structure of VIM-2 with 2-Mercaptomethyl-thiazolidine D-syn-1b Descriptor: (2~{S},4~{S})-2-ethoxycarbonyl-5,5-dimethyl-2-(sulfanylmethyl)-1,3-thiazolidine-4-carboxylic acid, Beta-lactamase VIM-2, FORMIC ACID, ... Authors: Hinchliffe, P, Spencer, J. Deposit date: 2020-08-02 Release date: 2021-01-20 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.45 Å) Cite: 2-Mercaptomethyl-thiazolidines use conserved aromatic-S interactions to achieve broad-range inhibition of metallo-beta-lactamases. Chem Sci, 12, 2021

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2020-08-02
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