Uveal melanoma (UM) is the most common primary intraocular carcinoma in adults. Cinobufagin, secreted by the Asiatic toad Bufo gargarizans, is a traditional Chinese medicine, widely used in tumor trea
Note that plasma, EES and intracellular concentrations are relative to volume fraction (i.e. plasma, EES, or cellular fraction). EES and intracellular concentrations would have to be multiplied by app
5 fluorouracil (5 FU), one of the most actively investigated anti-cancer drugs, is rapidly inactivated by the enzyme dihydropyrimidine dehydrogenase (DPD). ADH300004 blocks DPD. This study will examin