Cancer can develop due to abnormal cell proliferation in any body’s cells, so there are over a hundred different types of cancer, each with its distinct behavior and response to treatment. Therefore,
Iron is an essential micronutrient due to its involvement in many cellular processes including DNA replication and OXPHOS. Tumors overexpress iron metabolism linked proteins which allow for iron accum
To analyse the effect of Cinobufagin to human acute myeloid leukemia cell lines, HL60 and Kasumi-1. Overall design: 1) HL60 cells were treated with 100nM Cinobufagin for 24 hours 2) Kasumi-1 cells wer
Due to compromised homologous recombination (HR) repair, BRCA1- and BRCA2-mutated tumours accumulate DNA damage and genomic rearrangements conducive of tumour progression. To identify drugs that targe