Se-dependent glutathione peroxidase 1 activity in erythrocytes, total glutathione peroxidase 1 and Se-dependent glutathione peroxidase 4 activities in platelets: mean values at 0, 6, 10 and 12 weeks of supplementati

1All values are means ± SDs;
ranges in parentheses. Se-dependent activities in erythrocyte
samples were determined using tert-butyl hydroperoxide as the
substrate in the enzyme assay. Total GPx activities in platelet
samples were determined using cumene hydroperoxide as the substrate
in the enzyme assay [27], [29].
2numbers (n) for the GPx4 data are as
detailed in the text; placebo (n = 11), 50, 100
and 200 µg/day (n = 12, 14 and 19
respectively), unenriched (n = 14) and
Se-enriched (n = 9) due to undetectable GPx4
activity in the platelet enzyme extract compared with the control
enzyme extraction buffer. * P<0.05 for the comparison of
Time = 12 to Time = 0;
** P<0.005 for the comparison of
Time = 12 to Time = 0; #
P<0.005 for the comparison with unenriched onion.