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Pyridine derivative of the natural alkaloid Berberine as Human Telomeric G-quadruplex Binder

NIAID Data Ecosystem2026-05-01 收录

核酸靶向药物

G-四链体

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https://www.rcsb.org/structure/6S15 数据链接链接失效反馈

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Pyridine derivative of the natural alkaloid Berberine as Human Telomeric G-quadruplex Binder

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创建时间：

2024-01-24

DNA-蛋白质相互作用

G-四链体

DNA-protein interactions regulate critical biological processes. Identifying proteins that bind to specific, functional genomic loci is essential for understanding the underlying regulatory mechanisms

NIAID Data Ecosystem120

Confined space facilitates G-quadruplex formation 4

G-四链体

生物化学

Figure 5c-GQ wo NC in 40% BSA

DataCite Commons2020-09-02 更新80

MoRNiNG

RNA测序分析

G-四链体

MoRNiNG (Modification of RNAs in Natural rG4) records the putative G-quadruplex sequence (PQSs) containing the 9 types of RNA modification sites in 9 species. RNA types include mRNA, lncRNA, and miRNA

知名数据库50

Targeting aloe active compounds to c-KIT promoter G-quadruplex and comparative study of their anti proliferative property

抗癌药物

G-四链体

Small molecules targeting G-quadruplex of oncogene promoter is considered as a promising anticancer therapeutics approach. Natural aloe compounds aloe emodin, and its glycoside derivative aloe emodin-

DataCite Commons2022-11-16 更新90

The chemical nature of the interaction of natural ligands with G-quadruplexes

G-四链体

生物分子模拟

We provide here computational data corresponding to the manuscript "The chemical nature of the interaction of natural ligands with G-quadruplexes": 1_tleap: Topology and initial coordinate files fo

NIAID Data Ecosystem50

Pyridine derivative of the natural alkaloid Berberine as Human Telomeric G-quadruplex Binder

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