A cutting-edge approach unravels a novel role for CDK6 in leukemic progenitor cells
收藏干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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http://data.iscr.ac.cn/Article?id=4dba2e81bc5af91866b8139178dda528
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资源简介：
CDK6 induces a complex transcriptional program to block p53 in hematopoietic cells. CDK6 binds to the promoters of genes including p53-antagonists. Cells lacking CDK6 kinase function are required to mutate p53 to achieve a fully transformed immortalized state.
提供机构：
University of Veterinary Medicine
创建时间：
2022-02-20
