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Analysis of mRNA Changes in the prelimbic cortex of Rat with Chronic Neuropathic Pain

Alliance of Genome Resources2026-08-01 收录

神经病理性疼痛转录组

前边缘皮层基因表达

数据链接：

https://www.ncbi.nlm.nih.gov/gds/?term=GSE145226 数据链接链接失效反馈

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资源简介：

Neuropathic pain (NP) is a complex, chronic pain condition caused by injury or dysfunction affecting the somatosensory nervous system. This study aimed to identify crucial mRNA in prelimbic cortex (PL) involved in NP rats. mRNA microarrays were applied in the present study.

应用场景：

神经痛机制

神经病理性疼痛转录组

RAN-sequencing identifies the expression profile of lncRNAs, circRNAs, and mRNAs in the trigeminal ganglia of mice with or without trigeminal neuropathic pain induced by the chronic constriction injur

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Dynamics of global gene expression and chromatin accessibility of the peripheral nervous system in animal models of persistent pain. Dynamics of global gene expression and chromatin accessibility of the peripheral nervous system in animal models of persistent pain

表观遗传学

神经病理性疼痛转录组

Shared transcriptomic and epigenetic changes in two animal models improves our understanding of how chromatin structural changes alter dorsal root ganglion (DRG) gene expression under persistent pain

NIAID Data Ecosystem20

Sex-Specific Transcriptomic Signatures in Brain Regions Critical for Neuropathic Pain-Induced Depression

神经病理性疼痛转录组

抑郁症性别差异

Neuropathic pain is a chronic debilitating condition with a high comorbidity with depression. Clinical reports and animal studies have suggested that both the medial prefrontal cortex (mPFC) and the a

NIAID Data Ecosystem20

Whole genome transcription profiling of the L5 spinal nerve transection model of neuropathic pain in the rat, at different sequencing depths (RNA-Seq)

神经病理性疼痛转录组

RNA-seq差异表达分析

Poly(A) enriched RNA derived from the L5 DRG 7 days following L5-SNT and from naïve L5-DRG tissue was subjected to RNA-seq analysis at different sequencing depths 6 biological replicates (3 case – SNT

NIAID Data Ecosystem20

Whole genome transcription profiling of the L5 spinal nerve transection model of neuropathic pain in the rat, at different sequencing depths (Affymetrix exon-level)

神经病理性疼痛转录组

脊神经损伤模型

RNA derived from the L5 DRG 7 days following L5-SNT and from naïve L5-DRG tissue was subjected to microarray analysis and expression was determined at the exon and gene level 6 biological replicates (

NIAID Data Ecosystem20

Analysis of mRNA Changes in the prelimbic cortex of Rat with Chronic Neuropathic Pain

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