aOnly variants detected for more than one subject are shown. bNumber of subjects from whose data variant fitness was estimated. cIC50 values were measured in replicon cells; (L) variant with low-level

NIAID Data Ecosystem40

The baseline resistance-associated substitutions (RASs) and virologic failure in patients treated with sofosbuvir and ledipasvir.

病毒药物疗效

病毒耐药性分析

The baseline resistance-associated substitutions (RASs) and virologic failure in patients treated with sofosbuvir and ledipasvir.

Figshare2018-06-01 更新20

Phenotypic resistance of Y181C or K103N combined with different mutation sites in HIV-1 CRF_BC pol region to NNRTIs using an in vitro phenotypic assay.

抗生素敏感性测试

病毒耐药性分析

Note: aThe unit for the EC50 values of TMC-125 is nM, while that for the EC50 values of DLV, NVP and EFV is µM. Data were presented as the mean ± standard deviations of three separate determination. b

NIAID Data Ecosystem40

MinION amplicon sequencing of nsp12 in SARS-CoV-2 passaged in remdesivir

病毒基因组测序

病毒耐药性分析

Samples of SARS-CoV-2 passaged in cell culture with remdesivir. RNA from infected cells was sequenced over the SARS-CoV-2 nsp12 gene and sequenced by long-read amplicon sequencing on the Oxford Nanopo

NIAID Data Ecosystem30

Hepacivirus hominis Raw sequence reads. Hepacivirus hominis

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