Diamond2GO Database – Version 2025-07-28 (nr_clean_d2go)

This is the updated Diamond2GO reference database built on 28th July 2025. It is a DIAMOND-formatted protein database (`.dmnd`) consisting of over 34 million sequences derived from the NCBI `nr` dataset, filtered to include only those with Gene Ontology (GO) annotations. This version significantly improves sensitivity and annotation coverage compared to the original 2023 release used in the published D2GO manuscript. This database is intended for use with the Diamond2GO tool, which enables rapid GO-term annotation and enrichment analysis for high-throughput sequencing datasets. For reproducibility of results published using the earlier version (699,409 sequences), please refer to the [v1.0.0 release] https://github.com/rhysf/Diamond2GO/releases/tag/6a035ce