Gene Products and Targets

**Overview**
This data package contains datasets on gene products and targets including antigen-antibody responses, microarray protein expression, endogenous ligands and peptides, ligand molecules and interaction data for targets and ligands.

**Description**
This data package contains datasets from Guide to PHARMACOLOGY; an online, open-access portal to pharmacological information on all the human targets of prescription drugs, which is the product from the collaboration of the International Union of Basic and Clinical Pharmacology (IUPHAR) and the British Pharmacological Society (BPS). The information provided in this dataset shows the initial view or landing pages for each target family that provides expert-curated overviews of the key properties and selective ligands and tool compounds available. Additional information can be found also in other databases including Ensembl, UniProt, PubChem, ChEMBL, and DrugBank, as well as curated chemical information and literature citations in PubMed.

**Benefits**
- This data can be useful for further research and for education and training in pharmacological principles and techniques. information from this data package can be useful for researchers and students in pharmacology and drug discovery and provide the general public with accurate information on the basic science underlying drug action.

**License Information**
The use of John Snow Labs datasets is free for personal and research purposes. For commercial use please subscribe to the [Data Library](https://www.johnsnowlabs.com/marketplace/) on John Snow Labs website. The subscription will allow you to use all John Snow Labs datasets and data packages for commercial purposes.

**Included Datasets**
- [Pharmacology Complete List of Endogenous Ligands and Other Peptides](https://www.johnsnowlabs.com/marketplace/pharmacology-complete-list-of-endogenous-ligands-and-other-peptides)
- This dataset shows the complete list of Endogenous Ligands and Other Peptides from the Guide to PHARMACOLOGY; an online, open-access portal to pharmacological information on all the human targets of prescription drugs, which is the product from the collaboration of the International Union of Basic and Clinical Pharmacology (IUPHAR) and the British Pharmacological Society (BPS).
- [Pharmacology Complete List of Ligand Molecules](https://www.johnsnowlabs.com/marketplace/pharmacology-complete-list-of-ligand-molecules)
- This dataset shows the complete list of ligand molecules from the Guide to PHARMACOLOGY; an online, open-access portal to pharmacological information on all the human targets of prescription drugs, which is the product from the collaboration of the International Union of Basic and Clinical Pharmacology (IUPHAR) and the British Pharmacological Society (BPS).
- [Pharmacology Complete Target and Family List Identification](https://www.johnsnowlabs.com/marketplace/pharmacology-complete-target-and-family-list-identification)
- This dataset shows the complete target and family list from the Guide to PHARMACOLOGY; an online, open-access portal to pharmacological information on all the human targets of prescription drugs, which is the product from the collaboration of the International Union of Basic and Clinical Pharmacology (IUPHAR) and the British Pharmacological Society (BPS).
- [Pharmacology Interaction Data for Targets and Ligands](https://www.johnsnowlabs.com/marketplace/pharmacology-interaction-data-for-targets-and-ligands)
- This dataset shows the Interaction Data for Targets and Ligands from the Guide to PHARMACOLOGY; an online, open-access portal to pharmacological information on all the human targets of prescription drugs, which is the product from the collaboration of the International Union of Basic and Clinical Pharmacology (IUPHAR) and the British Pharmacological Society (BPS).
- [Pharmacology Mapping of Target ID and UniProt Accessions](https://www.johnsnowlabs.com/marketplace/pharmacology-mapping-of-target-id-and-uniprot-accessions)
- This dataset shows the Target Identification and UniProt Accessions from the Guide to PHARMACOLOGY; an online, open-access portal to pharmacological information on all the human targets of prescription drugs, which is the product from the collaboration of the International Union of Basic and Clinical Pharmacology (IUPHAR) and the British Pharmacological Society (BPS).
- [Pharmacology Mapping of Target and HGNC ID and Symbols](https://www.johnsnowlabs.com/marketplace/pharmacology-mapping-of-target-and-hgnc-id-and-symbols)
- This dataset shows the Target Identification and HGNC ID and Symbols from the Guide to PHARMACOLOGY; an online, open-access portal to pharmacological information on all the human targets of prescription drugs, which is the product from the collaboration of the International Union of Basic and Clinical Pharmacology (IUPHAR) and the British Pharmacological Society (BPS).

**Data Engineering Overview**
**We deliver high-quality data**
- Each dataset goes through 3 levels of quality review
- 2 Manual reviews are done by domain experts
- Then, an automated set of 60+ validations enforces every datum matches metadata & defined constraints
- Data is normalized into one unified type system
- All dates, unites, codes, currencies look the same
- All null values are normalized to the same value
- All dataset and field names are SQL and Hive compliant
- Data and Metadata
- Data is available in both CSV and Apache Parquet format, optimized for high read performance on distributed Hadoop, Spark & MPP clusters
- Metadata is provided in the open Frictionless Data standard, and its every field is normalized & validated
- Data Updates
- Data updates support replace-on-update: outdated foreign keys are deprecated, not deleted

**Our data is curated and enriched by domain experts**

Each dataset is manually curated by our team of doctors, pharmacists, public health & medical billing experts:
- Field names, descriptions, and normalized values are chosen by people who actually understand their meaning
- Healthcare & life science experts add categories, search keywords, descriptions and more to each dataset
- Both manual and automated data enrichment supported for clinical codes, providers, drugs, and geo-locations
- The data is always kept up to date – even when the source requires manual effort to get updates
- Support for data subscribers is provided directly by the domain experts who curated the data sets
- Every data source’s license is manually verified to allow for royalty-free commercial use and redistribution.

**Need Help?**
If you have questions about our products, contact us at [[e-mail]](mailto:[e-mail]).