Identification of TRIM24-dependent gene expression programs in prostate cancer cells.. Homo sapiens

In this experiment we are exploring which genes are regulated by TRIM24 in androgen-dependent and castration-resistant prostate cancer cells. Overall design: LNCaP and LNCaP-abl were transfected with siRNA targeting either control or TRIM24 for 48h. The cells were additionally stimulated with 10nM DHT or vehicle for 24h.