Summary of viral IRES elements investigated in this study.

NIAID Data Ecosystem2026-03-08 收录

病毒翻译调控

IRES元件分析

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Numbering of IRES nucleotides corresponds to genomic position based on the sequence of the full-length genome. Figure S1. IRES sequences are highlighted in IGR: intergenic region.

创建时间：

2013-12-20

A giant virus creates a subcellular environment to overcome the codon-tRNA mismatch [RNA-seq]

病毒翻译调控

病毒-宿主相互作用

A codon usage consonant with the cellular tRNA pool is important for efficient translation. However, Mimivirus, a giant DNA virus, relies on the host translation system of amoeba yet exhibits a codon

NIAID Data Ecosystem60

RiboSeq of BSR cells infected at MOI 3 with Theiler's murine encephalomyelitis virus, compared to mock-infected controls, harvested at 10 hpi. Fragments of lengths 35-65 nt purified.. RiboSeq of BSR cells infected at MOI 3 with Theiler's murine encephalomyelitis virus, compared to mock-infected controls, harvested at 10 hpi. Fragments of lengths 35-65 nt purified.

核糖体碰撞分析

病毒翻译调控

BSR cells were infected with the Cardiovirus B archetype, Theiler’s murine encephalomyelitis virus (TMEV), and mutants thereof, and subjected to ribosome profiling to analyse ribosome collision events

NIAID Data Ecosystem40

Cell Type-Specific Enhancement of Hepatitis C Virus Internal Ribosome Entry Site-Directed Translation due to 5′ Nontranslated Region Substitutions Selected during Passage of Virus in Lymphoblastoid Cells

病毒翻译调控

IRES内部核糖体进入位点

Low-level replication of hepatitis C virus (HCV) in cultured lymphoblastoid cells inoculated with H77 serum inoculum led to the appearance of new virus variants containing identical substitutions at t

PubMed Central20

Translational landscape of SARS-CoV-2 and infected cells

病毒翻译调控

宿主-病原体相互作用

Purpose: Numerous viruses manipulate the host translation machinery and specifically block host mRNA translation. The goal of this study is to define the translational landscape of SARS-CoV-2 and SARS

NIAID Data Ecosystem40

Ribosome profiling of A549 cells depleted of RPLP1 and RPLP2 and infected with DENV.

病毒翻译调控

核糖体功能

We used ribosome profiling to evaluate viral and cellular translation in RPLP1/2-depleted cells. This revealed that ribosomes pause in the sequence coding for the N-terminus of the envelope protein, i

NIAID Data Ecosystem30

Summary of viral IRES elements investigated in this study.

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